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Leon Aarons is a Professor and Director of Undergraduate Studies in the School
of Pharmacy and Pharmaceutical
Sciences, University of Manchester, UK.
His research interest is in population and physiologically-based
pharmacokinetics. He is co-editor of the Journal of Pharmacokinetics and Pharmacodynamics and executive editor of the British
Journal of Clinical Pharmacology.
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Dr Nick Holford is
Associate Professor of Clinical Pharmacology at the University
of Auckland. He is also an
Honorary Professor at the University
of Queensland and Adjunct
Professor at the University of California
San Francisco. His research interests include
population PKPD analyses of clinical trials of drugs, clinical trial
simulation, PKPD in neonates and children and rational approaches to
anti-cancer drug use.
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Mats Karlsson is
Professor of Pharmacometrics at the Faculty of
Pharmacy, Uppsala University, Sweden.
Since 1994, his research group has focused on methodological aspects of
nonlinear mixed effects model building and applied PK/PD modeling.
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France Mentré is
Professor of Biostatistics at the University Paris Diderot
(Paris 7), France. She heads an INSERM research team on Methods and Models
for therapeutic assessment in chronic diseases. She has worked on
development and application of methods for nonlinear mixed-effects models
in pharmacokinetics and pharmacodynamics for more
than 20 years.
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Stephen Duffull
is Professor of Clinical Pharmacy at the University
of Otago,
Dunedin, New Zealand.
He runs a modelling and simulation lab within the
School of Pharmacy.
Research interests include optimal design, MCMC methods particularly in
clinical toxicology and the influence of obesity on PKPD. He has been
involved in the area of PKPD and nonlinear mixed effects modelling for more than 10 years.
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